Nadolol beta-blocker therapy combined with ICD implantation prevented recurrence of arrhythmic events in a 25-year-old man with CPVT after sudden cardiac arrest.
Case Report (n=1)
No
This case highlights the critical role of a systematic diagnostic approach, particularly exercise stress testing, in young patients with sudden cardiac arrest to uncover rare inherited arrhythmias like CPVT that may be initially misdiagnosed as epilepsy.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but potentially life-threatening inherited arrhythmia disorder, often presenting in childhood or adolescence. Early and accurate diagnosis is critical, as untreated CPVT carries a high risk of sudden cardiac death, particularly in young individuals. This case underscores the importance of maintaining a high index of clinical suspicion and employing a systematic diagnostic approach. We highlight the value of integrating clinical history, family background, and targeted investigations in evaluating young adults presenting with sudden cardiac arrest. Prompt recognition and diagnosis of CPVT may be lifesaving and have significant implications for both patients and their families.
Dias et al. (2026) conducted a case report in A 25-year-old man with sudden cardiac arrest of unknown cause, formerly misdiagnosed with epilepsy, ultimately diagnosed with catecholaminergic polymorphic ventricular tachycardia (CPVT) (n=1). Nadolol beta-blocker therapy and implantable cardioverter-defibrillator (ICD) implantation was evaluated on Prevention of recurrence of ventricular arrhythmias and sudden cardiac arrest. Nadolol beta-blocker therapy combined with ICD implantation prevented recurrence of arrhythmic events in a 25-year-old man with CPVT after sudden cardiac arrest.
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