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February 8, 20260 citations

The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1.

YZYu ZhaoYCYun CaiJCJianzhong Chen

Key Points

  • Investigate the protective effect of resveratrol on lupus nephritis in MRL/lpr mice through Sirt1 activation.
  • Administered resveratrol to MRL/lpr mice
  • Monitored kidney function and health indicators
  • Examined Sirt1 signaling pathway activation
  • Resveratrol improved kidney health in treated mice
  • Activation of the Sirt1 pathway was observed
  • Protection against lupus nephritis symptoms was significant

Abstract

Res has a protective effect on MRL/lpr mice, and its mechanism may involve activation of the Sirt1 signaling pathway.

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Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/6988291e0fc35cd7a884930dhttps://doi.org/10.22038/ijbms.2025.90231.19451
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