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February 9, 2026Медицинский вестник МВД0 citations

Arrhythmogenic Dysplasia of the Right Ventricle: A Modern Genotype-Specific Approach to the Study of the Disease. Literature Review

VEV. EVDOKIMOVGAG. ARKAD'EVAKFK. FOMINA

Key Result

No clinical trial data or primary endpoint results were reported as the document is a literature review on arrhythmogenic dysplasia of the right ventricle focusing on genotype-specific approaches.

Key Points

  • The aim is to explore the various aspects of arrhythmogenic dysplasia of the right ventricle, focusing on genotype-specific characteristics.
  • Conducted a literature review on arrhythmogenic dysplasia of the right ventricle
  • Analyzed domestic and foreign studies related to the disease
  • Discussed specific features of pathogenesis and clinical presentation
  • Screening detects mutations in only 60-65% of patients
  • The disease presents variable clinical manifestations, including sudden cardiac death
  • A genotype-specific approach reveals distinct characteristics in pathogenesis

Structured PICO

P
Population
Patients with arrhythmogenic dysplasia of the right ventricle
I
Intervention
Genetic screening of known genes

Current genetic screening identifies mutations in 60-65% of patients with arrhythmogenic right ventricular dysplasia.

Limitations

  • No original clinical trial data presented
  • No quantitative clinical outcomes reported
  • Document is instructional/editorial in nature, lacking clinical evidence

Abstract

The paper presents a literature review on the arrhythmogenic dysplasia of the right ventricle – a family disease with variable clinical manifestations up to the sudden cardiac death. For the time being screening of all the known genes allows to detect mutations only in 60–65% patients with arrhythmogenic dysplasia of the right ventricle. Domestic and foreign literature on this issue has been studied. Specific features of pathogenesis and clinical presentation of this category of patients are described, genotypespecific approach to the study of the disease is considered

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Cite This Study

EVDOKIMOV et al. (2025) reported a review. No clinical trial data or primary endpoint results were reported as the document is a literature review on arrhythmogenic dysplasia of the right ventricle focusing on genotype-specific approaches.

synapsesocial.com/papers/698979d9f0ec2af6756e7d22https://doi.org/10.52341/20738080_2025_135_2_50
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