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February 9, 20261 citations

Scrolling Behavior of Descemet Membrane Endothelial Keratoplasty Grafts: Analysis of a Large Cohort of 3150 Grafts.

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TVThessalia VoulgariUSUrsula Schlötzer-SchrehardtJWJulia M. Weller

Key Points

  • To assess factors influencing the scrolling behavior of DMEK grafts in a large cohort.
  • Analysis of 3150 DMEK grafts
  • Evaluation of donor age and DM thickness
  • Correlation analysis of scroll formation
  • Younger donor tissues showed tighter scrolls
  • Correlation between age and scroll formation diminished in older donors
  • Thicker DM membranes were linked to looser scrolling patterns

Abstract

In this large cohort of DMEK grafts, donor age was confirmed as the most decisive factor influencing the scrolling behavior of DMEK grafts, with younger tissues demonstrating tighter scroll formation while the correlation gradually weakened in older donor groups. The DM thickness was confirmed as an independent contributor, as thicker membranes were associated with less tightly scrolled grafts.

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Cite This Study

Voulgari et al. (2026) studied this question.

synapsesocial.com/papers/698979f5f0ec2af6756e80d6https://doi.org/10.1097/ico.0000000000004108
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Retention of the Pre-Descemet’s Layer Reduces Endothelial Graft Scrolling: Digital Morphometric Analysis of Precut Endothelial Grafts2026
  2. 2Preoperative and perioperative factors that predict graft failure 1 year after Descemet membrane endothelial keratoplasty2026
  3. 3Influence of Donor Factors on Descemet Membrane Endothelial Keratoplasty (DMEK) Graft Preparation Outcome2024 · 8 citations
  4. 4Influence of Graft Unfolding Time During Descemet Membrane Endothelial Keratoplasty on Postoperative Endothelial Cell Loss and Visual Acuity2025
  5. 5Donor Tissue Impact on Descemet Membrane Endothelial Keratoplasty Graft Preparation and Clinical Outcome2026