This randomized trial assesses Spirulina's impact on psychological and clinical indicators in men under methadone therapy, suggesting potential benefits.
Key Points
This trial aims to evaluate Spirulina's effectiveness in improving psychological and cognitive outcomes in men undergoing methadone therapy.
Double-blind randomized clinical trial design
50 male patients undergoing methadone maintenance therapy
Participants received either Spirulina or placebo for 12 weeks
Psychological indicators measured using DASS-21 and sexual function assessed via IIEF
Cognitive performance evaluated with FAS test, IGT, and TMT
Spirulina significantly reduced anxiety and stress scores compared to the placebo (p < 0.05)
No significant differences observed in depression, sexual function, craving, or cognitive performance (p > 0.05)
Indicates potential of Spirulina as a supportive intervention in this population
Cite This Study
Asadolah‐poor‐kashi et al. (2026) studied this question.