Advances in organelle-targeted photosensitizer-mediated pyroptosis for photodynamic tumor therapy: overcoming immunological limitations

Key Points

• The review focuses on improving tumor treatment by using organelle-targeted methods to induce pyroptosis through photodynamic therapy.
• Review of current literature on organelle-targeted therapies and pyroptosis mechanisms.
• Analysis of immunological responses to photodynamic therapy in tumors.
• Evaluation of strategies to enhance treatment efficacy through targeted approaches.
• Organelle-targeted therapies show potential in activating pyroptosis, leading to enhanced tumor response.
• There is a significant improvement in overcoming immunosuppression associated with tumors using these methods.

Abstract