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February 11, 2026Asian Pacific Journal of Cancer Prevention0 citationsOpen Access

Towards Precision Oncology: A Predictive Nomogram Incorporating DPD and MTHFR for CapeOX Neoadjuvant Chemotherapy in Colorectal Cancer

ETElvida Christy Imelda TahiyaRLRonald Erasio LusikooyIPIlhamjaya Pattelongi

Key Points

  • The research aims to enhance the prediction of chemotherapy effectiveness in colorectal cancer using a novel nomogram.
  • Developed a predictive nomogram incorporating DPD and MTHFR biomarkers.
  • Evaluated the nomogram's effectiveness in estimating response to CapeOX neoadjuvant chemotherapy.
  • The nomogram significantly improved individualized response predictions.
  • Supports the idea of using biomarkers for tailored treatment strategies.

Abstract

A predictive nomogram that incorporated DPD and MTHFR has improved individualized estimation of CapeOX neoadjuvant chemotherapy response in CRC, supporting precision oncology strategies..

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Cite This Study

Tahiya et al. (2026) studied this question.

synapsesocial.com/papers/698c1bef267fb587c655dfb1https://doi.org/10.31557/apjcp.2026.27.2.731
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