Systemic Pharmacokinetic Principles of Therapeutic Peptides

Key Points

• The central aim is to understand how the size of peptide drugs affects their absorption and distribution in the body.
• Analyzed pharmacokinetic data of various peptide drugs
• Investigated physiological scaling patterns based on size
• Developed quantitative tools for drug discovery assessments
• Demonstrated that peptide pharmacokinetics follow predictable size-related patterns
• Provided tools that can improve the drug discovery process

Abstract