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February 12, 2026Molecular Nutrition & Food Research0 citationsOpen Access

Association Between Habitual Food Intake and Energy Metabolism‐Related Urine Metabolites in Female Soccer Players

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MNMaria B. A. NascimentoMGMaria M. S. GouveiaMSMaryssa P. P. Dos Santos

Key Points

  • This research aims to examine the relationship between habitual nutrient intake and urine metabolites related to energy metabolism in female soccer players.
  • Measured habitual food intake of thirteen players before the competitive season.
  • Collected pre- and post-match urine samples during five matches.
  • Analyzed urine metabolites using nuclear magnetic resonance (NMR).
  • Conducted univariate and multivariate analyses to assess associations.
  • Explored correlations between various nutrients and metabolites.
  • Identified positive associations between specific B vitamins, protein, and energy intake with certain metabolites like leucine and glucose.
  • Found inverse correlations between B vitamins and creatinine levels.
  • Noted that these associations reflect their roles in oxidative pathways within the TCA cycle and gluconeogenesis.

Abstract

ABSTRACT To assess the association between habitual nutrients intake and the energetic metabolism‐related metabolites found by nuclear magnetic resonance (NMR) in female soccer players’ urine.Thirteen female soccer players were measured for habitual food intake 11 days before the competitive season, and had urine samples collected pre‐ and post‐match during five matches of two simultaneous championships to be examined by NMR. Nutrients and metabolites were associated through univariate and multivariate analyses. B3, B6, Prot.kg and energy (Kcal.kg) with leucine; B1, B3, B6, energy (Kcal.kg) and Prot.kg with AHI, glucose, tyrosine; formate and 1‐Methylnicotinamide. In parallel, inverse correlations were observed between B3, B6, and Prot.kg with creatinine, B12 and 1‐Methylnicotinamide ( r ≥ 0.4; p < 0.05). In conclusion, it is possible to speculate that the herein described associations between metabolites and nutrients involved in energy metabolism seem to result from their participation in oxidative pathways, mainly in the TCA cycle and in gluconeogenesis.

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Cite This Study

Nascimento et al. (2026) studied this question.

synapsesocial.com/papers/698d6e055be6419ac0d5356bhttps://doi.org/10.1002/mnfr.70389
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