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February 13, 2026Open Access

Characteristics and prognosis of Epstein Barr virus-positive diffuse large B-cell lymphoma: a retrospective, single-center study

Puntos clave

To examine the characteristics and prognosis of Epstein Barr virus-positive diffuse large B-cell lymphoma in a specific cohort.
Retrospective analysis conducted in a single-center setting
Patient cohort comprised individuals diagnosed with EBV+ DLBCL
Characteristics assessed included β2-microglobulin levels and bone marrow involvement
Outcomes measured were progression-free survival (PFS) and overall survival (OS)
EBV+ DLBCL was predominantly non-GCB type
Elevated β2-microglobulin and bone marrow invasion were significant predictors of worse PFS
Elevated β2-microglobulin and anemia significantly predicted worse OS

Resumen

EBV+ DLBCL in this Chinese cohort was primarily non-GCB. Elevatedβ2-microglobulin and bone marrow invasion independently predicted inferior PFS, while elevatedβ2-microglobulin and anemia predicted inferior OS.

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