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Synapse
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Synapse
February 14, 2026JAMA0 citations

When Protocol Meets Reality

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WBWesley Burks

Key Points

  • To provide guidance for clinicians on adapting cognitive evaluations for patients with varying abilities, specifically in the context of Alzheimer's disease.
  • Descriptive narrative essay format
  • Illustrative case study involving the author's wife
  • Identification of three practical adaptation steps
  • Clinicians can enhance patient interactions by integrating understanding of patient abilities
  • Adaptations lead to more effective communication and assessment
  • Personal experiences illustrate the need for flexibility in clinical practices

Abstract

In this narrative medicine essay, a pediatrician and former medical school dean offers 3 steps for clinicians on how to adapt their cognitive evaluations to the abilities of their patients, in this case his wife who has stage 6 Alzheimer disease.

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Cite This Study

Wesley Burks (2026) studied this question.

synapsesocial.com/papers/699011172ccff479cfe57823https://doi.org/10.1001/jama.2026.0064
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical Research2024 · 30 citations
  2. 2Alzheimer Disease as a Clinical-Biological Construct—An International Working Group Recommendation2024 · 391 citations
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  4. 4Racial Disparity in Cerebrospinal Fluid Amyloid and Tau Biomarkers and Associated Cutoffs for Mild Cognitive Impairment2019 · 120 citations
  5. 5National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease2012 · 3,232 citations