PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 14, 2026The Journals of Gerontology Series A0 citations

Associations of unmet dental care needs due to cost with incident cardiovascular disease and dementia: a prospective study in the All of Us cohort

View Full Paper
MVMabeline VelezPBPeter ButoAPAnna M. Pederson

Key Points

  • This study aims to explore the relationship between unmet dental care needs due to cost and the incidence of cardiovascular diseases and dementia in older adults.
  • Analyzed data from the All of Us cohort comprising 98,787 older adults.
  • Followed participants for up to 5.3 years to observe incidents of myocardial infarction, stroke, heart failure, and dementia.
  • Used Cox proportional-hazards models to estimate hazard ratios for outcomes, adjusting for various covariates.
  • Individuals with unmet dental care needs due to cost had higher incidence rates of heart failure (HR = 1.45), myocardial infarction (HR = 1.37), and stroke (HR = 1.45).
  • The incidence of dementia was also higher in those reporting unmet dental needs (HR = 1.37).
  • Adjustments for socioeconomic and clinical factors attenuated these associations, but significant risks remained.

Abstract

Abstract Background Poor oral health among older adults may contribute to cardiovascular and dementia risk via systemic inflammation and cardiometabolic comorbidities. Financial constraints are a major driver of unmet dental care needs for older individuals. This study investigates whether having dental care needs that were unmet due to cost is associated with subsequent incidence of cardiovascular disease (CVD) or dementia among adults aged 55 and older. Methods Participants in the All of Us cohort (N = 98,787) who responded to a survey question on dental care needs that were unmet due to cost were followed up to 5.3 years via electronic health records for onset of myocardial infarction (MI), stroke, heart failure (HF), or dementia. We estimated outcome-specific hazard ratios (HRs), using Cox proportional-hazards models, adjusting for demographic, behavioral, and clinical covariates. Results After adjustment for demographic factors, individuals who reported unmet dental needs due to cost had relatively higher incidence of HF (HR = 1.45; 95% CI: 1.30, 1.63), MI (HR = 1.37; 95% CI: 1.17, 1.61), stroke (HR = 1.45; 95% CI: 1.24, 1.70), and dementia (HR = 1.37; 95% CI: 1.05, 1.76). These associations were attenuated after further adjusting for socioeconomic, behavioral, and clinical factors. We did not observe differences by gender, racial and ethnic identity, or periodontitis diagnosis. The estimated population attributable fraction suggested that eliminating financial barriers to dental care could prevent 2-4% of each outcome among older adults. Conclusion Financial barriers to dental care may be an important determinant of CVD and dementia among aging populations.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Velez et al. (2026) studied this question.

synapsesocial.com/papers/699011a12ccff479cfe58790https://doi.org/10.1093/gerona/glag023
Ask AI
Helpful
Bookmark
Share
View Full Paper