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February 16, 2026International Journal of Neuroscience

The correlation between YTHDF1 gene polymorphism and cognitive dysfunction after radiotherapy for glioma

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Authors

HZHuanfeng ZhuXSXiyun ShiDZDan Zong

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Overview

Analysis shows gene polymorphism impacts cognitive dysfunction in glioma after radiotherapy, suggesting genetic markers could guide patient outcomes.

Key Points

  • This research examines the link between YTHDF1 gene polymorphism and cognitive dysfunction post-radiotherapy in glioma patients.
  • Cohort of glioma patients receiving radiotherapy was analyzed.
  • Assessment of cognitive function was performed after treatment.
  • Evaluation of YTHDF1 gene polymorphism was conducted, focusing on rs6090311 G allele.
  • YTHDF1 overexpression correlates with cognitive dysfunction in glioma patients post-radiotherapy.
  • The rs6090311 G allele may serve as a protective genetic marker against cognitive decline.

Cite This Study

Zhu et al. (2026) studied this question.

synapsesocial.com/papers/69926503eb1f82dc367a0e82https://doi.org/10.1080/00207454.2026.2630961
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