Direct and indirect factors associated with health-related quality of life among PLHIV on second-line antiretroviral therapy at Dessie and Woldia Comprehensive Specialized Hospitals in Ethiopia: application of structural equation modelling
Cross-sectional study reveals psychosocial factors, including depression and social support, impact quality of life in PLHIV on antiretroviral therapy.
Key Points
This research aims to identify factors influencing health-related quality of life among people living with HIV receiving second-line antiretroviral therapy.
Conducted a cross-sectional study in Dessie and Woldia Hospitals, Ethiopia
Involved 825 people living with HIV selected through random sampling
Utilized WHOQOL-HIV BREF and PHQ-9 for data collection
Analyzed data using STATA version 17
Employed structural equation modelling for analysis
Mean health-related quality of life score was 48.7
Depression and internalized stigma negatively affected quality of life
Social support positively influenced social domain quality of life
Absence of opportunistic infection had a positive effect on quality of life
Functional status was linked to lower physical domain quality of life score