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February 19, 2026BMC Gastroenterology0 citationsOpen Access

Global and regional disparities in the burden of disease and risk factors between pancreatitis and pancreatic cancer: a systematic analysis for the global burden of disease study

MGMikiyas Amare GetuJLJun S. LiuLMLi Ma

Key Points

  • The analysis aims to compare disease burden and risk factors between pancreatitis and pancreatic cancer globally and regionally.
  • Conducted systematic analysis using data from the global burden of disease study.
  • Evaluated incidence, prevalence, mortality, and DALY burden associated with pancreatitis and pancreatic cancer.
  • Assessed the impact of modifiable risk factors on both conditions.
  • Pancreatitis has higher incidence and prevalence compared to pancreatic cancer.
  • Pancreatic cancer shows a higher mortality burden than pancreatitis.
  • Modifiable risk factors like alcohol, smoking, and obesity are significantly linked to both diseases.

Abstract

Pancreatitis exhibited a greater incidence, prevalence, and DALY burden, whereas pancreatic cancer carried a disproportionately higher mortality burden. Modifiable risk factors - including alcohol consumption, smoking, BMI, obesity, hypertension, and hypercholesterolemia were strongly associated with both conditions, underscoring the need for targeted prevention strategies and improved disease management to reduce the global burden.

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Cite This Study

Getu et al. (2026) studied this question.

synapsesocial.com/papers/6996a768ecb39a600b3ed096https://doi.org/10.1186/s12876-026-04668-x
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