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February 19, 2026BMC Neurology0 citationsOpen Access

Clinical outcomes, serum IgG changes, and follow-up observations in the treatment of anti-AChR antibody-positive generalized myasthenia gravis with Efgartigimod

JFJingting FuXZXianzhao ZhengXMXiaoli Ma

Key Points

  • The study aims to evaluate the effectiveness of efgartigimod in treating generalized myasthenia gravis and its impact on serum IgG levels.
  • Administration of efgartigimod alongside immunosuppressants.
  • Monitoring clinical symptoms and serum IgG levels in participants.
  • Follow-up observations to assess long-term control of the disease.
  • Significant improvement in clinical symptoms was observed in patients.
  • Serum IgG levels were notably reduced with efgartigimod treatment.
  • Long-term disease control is enhanced when used in combination with immunosuppressants.

Abstract

Efgartigimod has been shown to rapidly improve clinical symptoms in patients with generalised myasthenia gravis, while also significantly reducing serum IgG levels. When used alongside immunosuppressants, it can help to maintain long-term control of the disease.

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Cite This Study

Fu et al. (2026) studied this question.

synapsesocial.com/papers/6996a788ecb39a600b3ed487https://doi.org/10.1186/s12883-026-04726-7
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