PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 19, 2026SHILAP Revista de lepidopterología0 citationsOpen Access

Prognostic Biomarkers of Systemic Inflammation in Neuroendocrine Neoplasms

Connecting systemic inflammation to prognosis in neuroendocrine neoplasms: a biomarker-based approach

View Full Paper

Authors

AIAndreea IlieșiuAGAncuța-Augustina Gheorghişan-GǎlǎțeanuDȚDana Antonia Țǎpoi

Discussion

Loading...

Member takes

Overview

Retrospective analysis connects inflammatory biomarkers with mortality in neuroendocrine neoplasms, suggesting improved risk assessment.

Key Points

  • This analysis aims to identify cost-effective biomarkers that correlate with prognosis in neuroendocrine neoplasms.
  • Conducted a retrospective analysis of 60 patients with neuroendocrine neoplasms
  • Analyzed blood counts to derive neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII)
  • Used logistic regression models to evaluate prognostic significance in relation to demographic and clinical features.
  • 38.3% of patients died during follow-up
  • Low lymphocyte counts and elevated PLR, NLR, and SII were significant predictors of mortality
  • Advanced age, poorly differentiated NEC histology, and elevated SII were linked to increased mortality in multivariate analysis.
Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Ilieșiu et al. (2026) studied this question.

synapsesocial.com/papers/6996a798ecb39a600b3ed726https://doi.org/10.3389/fmed.2026.1728726
Ask AI
Helpful
Bookmark
Share
View Full Paper