Cost of hepatic decompensation and liver transplantation events in primary biliary cholangitis: a retrospective observational study

Aim: Complications of primary biliary cholangitis (PBC) are proposed to confer substantial economic burden to patients and healthcare systems. This retrospective observational study evaluated the cost of PBC-related hepatic decompensation and liver transplantation using a large administrative claims database. Materials for events without readmission, the mean cost was 43, 404. 81. The mean total cost of liver transplantation per patient was 328, 336. 60. The mean cost per patient was highest for the hospitalization for transplantation (226, 908. 70). Conclusion: This comprehensive cost analysis demonstrates the high-cost burden of PBC disease progression. Appropriate patient management may help to mitigate the economic burden of PBC-related hepatic decompensation and liver transplantation.