A peak workload ≤52% of predicted during preoperative exercise testing was associated with a significantly higher rate of postoperative cardiopulmonary complications (58% vs. 33%, p=0.001).
Cohort (n=226)
Does a peak workload ≤52% of predicted during preoperative CPET predict postoperative cardiopulmonary complications in high-risk patients undergoing lung cancer resection?
In high-risk patients undergoing lung cancer resection, a peak workload ≤52% of predicted during preoperative CPET is associated with significantly higher rates of 30-day postoperative cardiopulmonary complications and longer hospital stays.
Estimación del efecto: AUC 0.59 (95% CI 0.51-0.67)
Tasa de eventos absoluta: 58% vs 33%
valor p: p=0.001
Objectives: To determine whether peak workload (Wpeak), expressed as a percentage of predicted value during a cardiopulmonary exercise test (CPET), can predict postoperative cardiopulmonary complications in high-risk patients undergoing lung cancer resection. Methods: A retrospective cohort study was conducted on 226 consecutive patients who underwent anatomical lung resection (lobectomy or segmentectomy) for non-small cell lung cancer between 2013 and 2017. All patients were considered high-risk, with preoperative FEV₁ and DLco 52%. Conclusions: Wpeak ≤52% of predicted was associated with increased risk of postoperative complications and longer hospitalization. Although the discriminatory ability was modest (AUC 0.59), Wpeak ≤52% predicted was associated with higher postoperative complications and may serve as a complementary tool for risk stratification, especially in resource-limited settings. Further prospective validation is warranted.
Rodó-Pin et al. (Mon,) conducted a cohort in Non-small cell lung cancer (n=226). Peak workload (Wpeak) ≤52% predicted vs. Wpeak >52% predicted was evaluated on Occurrence of cardiopulmonary complications within 30 days postoperatively (AUC 0.59, 95% CI 0.51-0.67, p=0.001). A peak workload ≤52% of predicted during preoperative exercise testing was associated with a significantly higher rate of postoperative cardiopulmonary complications (58% vs. 33%, p=0.001).