This prospective study demonstrates the N-NOSE method's ability to predict chemotherapy outcomes in breast cancer, highlighting its potential as a reliable diagnostic tool.
Key Points
To evaluate the predictive ability of the N-NOSE method for neoadjuvant chemotherapy response in breast cancer patients.
Enrolled 36 breast cancer patients for neoadjuvant chemotherapy and surgery.
Collected urine samples at three time points: before chemotherapy, before surgery, and four weeks post-surgery.
Conducted chemotactic assays using C. elegans and calculated the chemotaxis index and Index Reduction Score.