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February 19, 2026Annals of Medicine0 citationsOpen Access

Micro/nanoplastics induce thyroid follicular cell pyroptosis to trigger thyrotoxicity by activating NF-κB signaling

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FFFangda FuYCYuying ChenHLHuan Luo

Key Points

  • This research aims to elucidate the mechanisms by which micro/nanoplastics cause thyroid toxicity through follicular cell pyroptosis.
  • Investigated the effects of micro/nanoplastics on thyroid follicular cells
  • Analyzed pyroptosis activation mechanisms
  • Examined NF-κB signaling pathway involvement
  • Identified pyroptosis as a key mechanism in thyroid cell toxicity
  • Demonstrated activation of NF-κB signaling in response to micro/nanoplastics
  • Highlighted the adverse impacts of environmental plastic exposure on thyroid health

Abstract

Collectively, these findings provide novel mechanistic insights into MNP-induced thyroid toxicity and highlight the critical role of follicular cell pyroptosis, contributing to our understanding of the adverse health consequences associated with environmental plastic pollution.

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Cite This Study

Fu et al. (2026) studied this question.

synapsesocial.com/papers/6996a8c7ecb39a600b3efd5chttps://doi.org/10.1080/07853890.2026.2624175
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