Why the study?
Patients with Wolff-Parkinson-White syndrome present a significant challenge during anesthesia due to the latent risk of life-threatening arrhythmias triggered by perioperative stress, surgical stimuli, or anesthetic induction and emergence.
Population
A 53-year-old patient with WPW syndrome and a potentially malignant renal tumor
Design
Case report
Key result
Tailored general anesthesia management with Propofol, Fentanyl, Desflurane, and Dexmedetomidine enabled uneventful radical nephrectomy in a 53-year-old female with WPW syndrome despite no prior accessory pathway ablation.
Authors
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May inform anesthetic choices in unablated WPW; hypothesis-generating and requires validation before practice change.
Case Report (n=1)
No
Individualized anesthetic management using propofol, fentanyl, and dexmedetomidine with deep extubation allowed for a safe radical nephrectomy in a patient with unablated Wolff-Parkinson-White syndrome.
Rentería et al. (2026) conducted a case report in 53-year-old female patient with Wolff-Parkinson-White syndrome presenting with symptomatic precordial pain and palpitations undergoing urgent radical nephrectomy for suspected malignant renal tumor (n=1). General anesthesia with tailored anesthetic management using Propofol, Fentanyl, Desflurane (0.6 MAC), Dexmedetomidine infusion, Rocuronium, and Sugammadex was evaluated on Favorable perioperative outcome without development of tachyarrhythmias or complications. Tailored general anesthesia management with Propofol, Fentanyl, Desflurane, and Dexmedetomidine enabled uneventful radical nephrectomy in a 53-year-old female with WPW syndrome despite no prior accessory pathway ablation.
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