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February 21, 2026Cureus0 citationsOpen Access

Ogilvie Syndrome: A Therapeutic Challenge

ARAna Sofia ReisAAAna Rita AntunesLSLígia R Santos

Key Points

  • To explore the management of Ogilvie syndrome, highlighting effective therapeutic strategies.
  • Case presentation of an Ogilvie syndrome patient
  • Review of current literature on management approaches
  • Discussion on therapeutic inertia and medical education
  • Successful application of conservative management techniques
  • Endoscopic and pharmacologic interventions demonstrated effectiveness
  • Identification of gaps in current evidence for treatment guidelines

Abstract

Ogilvie syndrome, or acute colonic pseudo-obstruction, is a rare disorder characterized by colonic dilation without mechanical obstruction. It primarily affects elderly or hospitalized patients and can lead to serious complications, including ischemia and perforation. Management typically begins with conservative measures, but refractory cases may require endoscopic or pharmacologic interventions. Current literature lacks robust evidence to guide the optimal therapeutic approach. We present a case that demonstrates practical management strategies, mitigates therapeutic inertia, and supports continuous medical education.

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Cite This Study

Reis et al. (2026) studied this question.

synapsesocial.com/papers/69994a7f873532290d01ee40https://doi.org/10.7759/cureus.103754
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