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February 21, 2026Cureus0 citationsOpen Access

Severe Varicella Pneumonia in an Immunocompetent Adult Requiring Intensive Care Management: A Case Report

MGManal El GoubiMMMohmmed MoussaouiKKKhalid K Khaleq

Key Points

  • To highlight the severe complications of varicella pneumonia in previously healthy adults and the importance of prompt treatment.
  • Case report of a 32-year-old male with varicella pneumonia requiring ICU admission.
  • Chest CT imaging assessed for pneumonia-related complications.
  • Antiviral treatment initiated with intravenous acyclovir followed by oral valacyclovir.
  • The patient developed acute hypoxemic respiratory failure three days after a varicella rash.
  • CT scan revealed bilateral ground-glass opacities and focal consolidation.
  • Prompt antiviral therapy led to favorable clinical and radiological outcomes.

Abstract

Varicella is usually a mild childhood disease; however, primary infection in adults may lead to severe complications, particularly varicella pneumonia. We report the case of a 32-year-old previously healthy male admitted to the intensive care unit with acute hypoxemic respiratory failure occurring three days after the onset of a diffuse vesicular rash. Chest CT demonstrated bilateral ground-glass opacities with focal consolidation consistent with viral pneumonia. The diagnosis was established based on typical cutaneous findings, epidemiological exposure, and compatible imaging results. Early treatment with intravenous acyclovir followed by oral valacyclovir resulted in favorable clinical and radiological outcomes. This case emphasizes the importance of early recognition and prompt antiviral therapy to improve prognosis, even in immunocompetent adults without classical risk factors.

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Cite This Study

Goubi et al. (2026) studied this question.

synapsesocial.com/papers/69994a7f873532290d01efe9https://doi.org/10.7759/cureus.103763
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Also Consider

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  1. 1Early Treatment with Acyclovir for Varicella Pneumonia in Otherwise Healthy Adults: Retrospective Controlled Study and Review1990 · 214 citations
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  4. 4Acute respiratory distress syndrome caused by varicella pneumonia in immunocompetent adult: Clinical case2021 · 7 citations
  5. 5Varicella pneumonia in adults2003 · 182 citations