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February 21, 2026JGH OpenOpen Access

Pancreatic Involvement in von Hippel Lindau Disease: A Single‐Center Experience

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Authors

ABAli Emre BardakCYCeren YazkacZİZülal İstemihan

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Overview

Retrospective observational study describes pancreatic manifestations in VHL patients, suggesting the need for systematic screening.

Key Points

  • The aim is to characterize the clinical features and pancreatic manifestations in patients with Von Hippel Lindau disease.
  • Retrospective observational study conducted at a single center.
  • Inclusion of 15 patients with confirmed pancreatic involvement.
  • Data collected from electronic health records regarding demographics and clinical findings.
  • Analysis includes imaging studies, cyst fluid analysis, and pathology from fine needle aspiration.
  • 13 patients had multiple pancreatic cysts; 1 patient had a pancreatic neuroendocrine tumor (PNET).
  • Most cysts observed in the body and neck of the pancreas; largest cysts were generally located in the head.
  • Cysts were primarily serous cystadenomas; one cyst classified as a pseudocyst.
  • Incidence of pancreatic insufficiency observed in two patients, associated with pancreatic parenchyma loss.

Cite This Study

Bardak et al. (2026) studied this question.

synapsesocial.com/papers/69994ad4873532290d01f2e8https://doi.org/10.1002/jgh3.70360
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