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February 21, 2026Journal of the International Society of Sports NutritionOpen Access

Anti-inflammatory effects of nicotinamide mononucleotide (NMN) in human skeletal muscle after BFR-exercise

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Authors

DYDailin YangKCKuo-Ching ChaoHYHui-Tai Yang

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Overview

Observational study shows NMN supplementation reduces inflammation in skeletal muscle, suggesting potential for recovery enhancement.

Key Points

  • The aim is to investigate how NMN supplementation affects inflammation in human skeletal muscle following exercise.
  • Administered NMN supplementation after exercise.
  • Measured inflammation and mitochondrial replenishment in skeletal muscle tissues.
  • Analyzed the signaling pathways involved in the response.
  • NMN supplementation significantly inhibited inflammatory signaling in the muscle.
  • Suppressed mitochondrial replenishment from phagocytes was observed.
  • Potential implications for muscle repair processes were noted.

Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69994bdd873532290d01fe62https://doi.org/10.1080/15502783.2026.2632284
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