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February 21, 2026RSC Advances0 citationsOpen Access

Aqueous glyoxal: a versatile synthon in heterocyclic synthesis

AOAbolfazl OlyaeiMSMahdieh Sadeghpour

Key Points

  • The review aims to summarize the applications of aqueous glyoxal in creating diverse heterocyclic compounds.
  • Reviewed protocols for using aqueous glyoxal in organic synthesis.
  • Focused on generating five- and six-membered heterocycles.
  • Analyzed existing literature on glyoxal applications.
  • Identified aqueous glyoxal as a key reagent for various reactions.
  • Showed its effectiveness in forming diverse molecular frameworks.
  • Demonstrated practical applications in synthesizing complex heterocycles.

Abstract

This review highlights the applications of aqueous glyoxal as a versatile reagent in organic synthesis, with a focus on protocols for generating diverse molecular frameworks, including five- and six-membered heterocycles.

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Cite This Study

Olyaei et al. (2026) studied this question.

synapsesocial.com/papers/69994c6f873532290d020dbbhttps://doi.org/10.1039/d5ra08496b
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