What question did this study set out to answer?

To examine the relationship between maternal omega-3 status and the risk of preterm birth.

February 22, 2026

Maternal omega-3 status and preterm birth: real-world pathology identifies an exploratory mid-range pattern

JAJessica AntonovichUniversity of Newcastle Australia ACAmanda CaswellJohn Hunter Hospital HTHuy Q. TranUniversité Paris-Saclay

Puntos clave

To examine the relationship between maternal omega-3 status and the risk of preterm birth.
Analyzed maternal omega-3 status using red blood cell fatty acid analysis.
Investigated real-world pathology data to establish baseline risk patterns.
Explored associations with gestational age and preterm birth outcomes.
Identified a mid-range pattern of omega-3 status associated with preterm birth risk.
Established uncertainty in current laboratory thresholds based on DHA supplementation trials.

Resumen

Background: Maternal omega-3 status is measurable through red blood cell fatty acid analysis; however, current laboratory thresholds are mostly derived from DHA supplementation trials rather than real-world pathology datasets, leaving uncertainty around baseline risk patterns. Clarifying how omega-3 categories relate to gestational age (GA) may support improved preterm birth (PTB) risk identification. 1-3

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