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February 22, 2026Magnetic Resonance in Chemistry0 citations

New Alkaloid From the Marine‐Derived Fungus Aspergillus sp. MF01

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XZXiu‐Rong ZhouYWYan‐Wen WuJWJun‐Yi Wu

Key Points

  • To isolate and evaluate the antimicrobial activity of a new alkaloid from a marine-derived fungus.
  • Isolation of compounds from Aspergillus sp. MF01
  • Structural elucidation using NMR, HRESIMS, and ECD
  • Evaluation of antimicrobial activity against Gram-positive bacteria
  • Isolated two compounds, including the new alkaloid aspergilloid A
  • Aspergilloid A exhibited weak antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis at 1 mg/mL

Abstract

ABSTRACT Two compounds, including one new alkaloid, namely, aspergilloid A ( 1 ), together with one known compound ( 2 ), were isolated from the sponge‐derived fungus Aspergillus sp. MF01. The structure of one undescribed compound was elucidated by NMR, HRESIMS, and electronic circular dichroism (ECD) diffraction spectroscopy. All the isolated compounds were evaluated for their antimicrobial activities. Compound 1 showed weak antibacterial activity against Gram‐positive bacteria Staphylococcus aureus and Staphylococcus epidermidis at 1 mg/mL.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/699a9d27482488d673cd2e0chttps://doi.org/10.1002/mrc.70088
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