ABSTRACT Kasabach-Merritt syndrome (KMS) is a rare, life-threatening coagulopathy associated with kaposiform hemangioendothelioma and tufted angioma, typically seen in infants and rarely in adults. It is thought to result from platelet and coagulation factor sequestration within vascular lesions, leading to severe bleeding. We report a case of a 70-year-old woman with KMS presenting with rectal bleeding. Despite limited access to desmopressin, which had effectively controlled her symptoms, she experienced recurrent bleeding and ultimately succumbed to gastrointestinal hemorrhage. This case underscores the challenges of managing KMS in adults and highlights the importance of multidisciplinary coordination and consistent follow-up.
Menon et al. (Sun,) studied this question.