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February 22, 2026Food and Chemical ToxicologyOpen Access

Chemical Profiling and Toxicological Assessment of Refined Idesia polycarpa Maxim Oil: Acute and Genotoxicity Evaluations

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Authors

ZZZhaoXue ZhongJWJinhua WangJYJinxiang Yang

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Overview

Chemical profiling and toxicological assessments demonstrate refined Idesia polycarpa oil's safety for food use, implying its viability as an edible oil.

Key Points

  • The objective is to evaluate the safety and chemical composition of refined Idesia polycarpa Maxim oil.
  • GC-MS and GC-FID chemical characterization of refined Idesia polycarpa Maxim oil
  • Acute oral toxicity testing in KM mice
  • Ames assay for mutagenicity evaluation
  • Mammalian micronucleus test
  • Spermatogonial chromosomal aberration tests
  • Refined Idesia polycarpa Maxim oil is classified as non-toxic (LD 50 > 10.0 g/kg)
  • No mutagenicity was observed in Ames tests
  • Micronucleus frequencies showed no increase versus controls (p > 0.05)
  • No significant differences in chromosomal aberration rates from controls

Cite This Study

Zhong et al. (2026) studied this question.

synapsesocial.com/papers/699a9d50482488d673cd3238https://doi.org/10.1016/j.fct.2026.116023
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