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February 23, 2026Current Obesity ReportsOpen Access

Obesity in Type 1 Diabetes: Moving Beyond the “Lean” Disease Paradigm to Understand Risk, Complications, and Treatment

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Authors

ATAnastasios TentolourisTKTheocharis KoufakisEFEvangelos Fousteris

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Overview

This narrative review explores obesity's complications in type 1 diabetes, highlighting management strategies and treatment implications.

Key Points

  • The review aims to understand the relationship between obesity and type 1 diabetes, including risks and treatment options.
  • Narrative review synthesizing current evidence on obesity in type 1 diabetes
  • Analysis of mechanisms linking excess adiposity with type 1 diabetes
  • Discussion on obesity-related complications and management strategies
  • Excess adiposity in type 1 diabetes approaches general population prevalence
  • Higher adiposity correlates with poorer glycemic control and increased risk of complications
  • Adjunct therapies like liraglutide and semaglutide show promise but have risks of hypoglycemia

Cite This Study

Tentolouris et al. (2026) studied this question.

synapsesocial.com/papers/699bee1c1c6c6bad5397fe16https://doi.org/10.1007/s13679-026-00693-9
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