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February 24, 2026Annals of Pharmacotherapy0 citations

Efficacy and Safety of GLP-1 Receptor Agonists for the Management of Antipsychotic-Induced Weight Gain

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SPSarah PascaleJRJustin P. Reinert

Key Points

  • To evaluate the effectiveness and safety of GLP-1 receptor agonists in managing weight gain associated with antipsychotic use.
  • Reviewed existing literature on GLP-1 receptor agonists
  • Analyzed effects on weight loss in patients using antipsychotics
  • Assessed safety profiles of the medications
  • GLP-1 receptor agonists led to significant weight loss in patients
  • Improved management of antipsychotic-induced weight gain
  • Minimal safety concerns were reported

Abstract

The use of certain GLP-1 agonists may be considered to help promote weight loss in patients experiencing antipsychotic-induced weight gain.

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Cite This Study

Pascale et al. (2026) studied this question.

synapsesocial.com/papers/699d405ade8e28729cf65501https://doi.org/10.1177/10600280251414107
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