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February 25, 20260 citationsOpen Access

Computed Tomographic Evaluation of Acute Hemorrhagic Stroke Volume and its Relationship with Clinical Outcome

YTYetunde F. TaiwoAGAnthony Epga GabkwetMOMargaret Isioma Ojeahere

Key Points

  • To determine the correlation between hemorrhagic stroke lesion volume and clinical outcomes at 30 days post-stroke.
  • Recruited acute hemorrhagic stroke patients over 18 months.
  • Measured intracerebral hemorrhage (ICH) volume and affected sites using computed tomography.
  • Correlated ICH volume with patients' modified Rankin Scale (mRS) assessments at 30 days post-stroke.
  • Utilized Student’s t-test and logistic and linear regression analyses.
  • Included 44 patients with a mean ICH lesion volume of 30.8 ml.
  • Patients with favorable mRS outcomes had a mean volume of 32.2 ml, while those with unfavorable outcomes had 29.2 ml.
  • Regression analyses did not show significant correlation between lesion volume and mRS outcomes (P=0.982) or between volume and patient survival (P=0.868).

Abstract

Background: Hemorrhagic stroke outcome has been poorly studied in this region despite being a significant cause of morbidity and mortality. The use of computed tomography to assess the volumes of lesion, the sites of the brain affected, and their relationship with patients’ clinical outcome will add to the body of knowledge in the management of hemorrhagic stroke. Objectives: The objectives of this study are to determine if the volume of hemorrhagic stroke lesion correlates with patient clinical outcome at 30 days poststroke. Materials and Methods: Acute hemorrhagic stroke patients were recruited consecutively over 18 months. Intracerebral hemorrhage (ICH) volume and the sites affected were correlated with the patients’ modified Rankin Scale (mRS) assessment outcome at 30 days poststroke. The mRS scores of (0–3) were regarded as favorable and (4–6) as unfavorable. Student’s t‑test, logistic, and linear regression analyses were done using the Statistical Package for the Social Sciences software version 20.0, level of significance was set at P ≤ 0.05. Results: Forty‑four patients were included in the study. Overall, mean (standard deviation) ICH lesion volume of 30.8 (33.2) ml was observed. Mean volumes of 32.2 (35.7) ml and 29.2 (30.9) ml were seen in patients with favorable and unfavorable outcomes, respectively. Linear and logistic regression analyses of the volume of the lesion on mRS outcome and patient outcome (alive vs. dead) were not statistically significant with P values of 0.982 and 0.868, respectively. Conclusion: Hemorrhagic stroke lesion volume though important in the assessment of patients does not significantly correlate with patient outcome at 1‑month poststroke.

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Cite This Study

Taiwo et al. (2026) studied this question.

synapsesocial.com/papers/699e9152f5123be5ed04ec34https://doi.org/10.82339/jrmt.vol1no2.78
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