Hypoxic-hypocapnic red blood cells in PAGGSM additive solution before and after gamma irradiation show improved metabolism.

Key Points

• Investigate the metabolic effects of hypoxic-hypocapnic conditions on red blood cells stored in PAGGSM before and after gamma irradiation.
• Examined red blood cells in PAGGSM additive solution
• Assessed ATP and 2,3-DPG levels
• Evaluated RBC quality post gamma irradiation
• Increased ATP and 2,3-DPG levels in stored red blood cells
• Fulfilled RBC quality criteria for other parameters
• Support for clinical use in optimizing RBC transfusion quality