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Synapse
February 26, 2026ICT Express0 citationsOpen Access

Fusion of bidirectional neural networks decision for a high accuracy breast cancer detection based on DNA biomarker

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RRRoslidar RoslidarQAQurrata A’yuniMZM. Zulhamsyah

Key Points

  • The research aims to enhance breast cancer classification accuracy using deep learning techniques applied to DNA biomarkers.
  • Applied decision fusion method using Bidirectional Long Short-Term Memory and Gated Recurrent Unit.
  • Collected and pre-processed 1217 DNA sequences from the Protein Data Bank.
  • Used fast Fourier transform and BLAST for similarity analysis, transforming sequences into numerical representations.
  • Achieved a classification accuracy of 99.18% for DNA biomarkers.
  • Successfully distinguished between normal and cancer-related protein sequences.

Abstract

This study investigates the potential of deep learning-based sequence modelling for breast cancer classification using DNA biomarker data. A decision fusion method Bidirectional Long Short-Term Memory and Gated Recurrent Unit is proposed to distinguish between normal and cancer-related protein sequences. A total of 1217 sequences were collected from the Protein Data Bank, pre-processed using multiple alignment of fast Fourier transform and basic local alignment search tool for similarity analysis, and transformed into numerical representations using integer and label encoding. The results demonstrate that the rule-based decision fusion approach has effectively classified DNA biomarkers with an accuracy rate of 99.18%.

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Cite This Study

Roslidar et al. (2026) studied this question.

synapsesocial.com/papers/699f95951bc9fecf3dab3833https://doi.org/10.1016/j.icte.2026.02.007
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