The existing SSI risk indices showed poor discrimination with C-statistics up to 0.60 and 0.58 in the overall and cardiac surgery cohorts respectively, while the newly developed prediction model had a poor discriminatory ability (C-statistic 0.67) but good calibration for predicting SSI within 90 days after surgery in a 9657-patient European adult surgical cohort.
Observational (n=9,657)
Sí
Existing surgical site infection risk indices, including those specifically designed for cardiac surgery, demonstrated poor discrimination and overestimated risk in a contemporary European surgical cohort.
Estimación del efecto: C-statistic 0.60 for NNIS in overall cohort; C-statistic 0.58 for IRIC in cardiac sub-cohort; newly developed multivariable model C-statistic 0.67 (95% CI 0.64 - 0.69) (95% CI 95% CI 0.64 - 0.69 for new model)
The SSI risk indices had comparable discrimination when clustering was taken into account, but suboptimal calibration in our cohorts compared with their derivation cohorts.
Troeman et al. (Mon,) conducted a observational in surgical site infection (SSI) in adults after surgery (n=9,657). Risk indices for SSI prediction (NNIS risk index, NNIS index improved for cardiac patients, Australian clinical risk index, Infection risk index in cardiac surgery, Risk index A, Risk index B) and a newly developed multivariable risk prediction model vs. None (validation of existing risk indices and comparison among them) was evaluated on Occurrence of a surgical site infection (SSI) of any microbial etiology up to 90 days post-surgery (C-statistic 0.60 for NNIS in overall cohort; C-statistic 0.58 for IRIC in cardiac sub-cohort; newly developed multivariable model C-statistic 0.67 (95% CI 0.64 - 0.69), 95% CI 95% CI 0.64 - 0.69 for new model). The existing SSI risk indices showed poor discrimination with C-statistics up to 0.60 and 0.58 in the overall and cardiac surgery cohorts respectively, while the newly developed prediction model had a poor discriminatory ability (C-statistic 0.67) but good calibration for predicting SSI within 90 days after surgery in a 9657-patient European adult surgical cohort.