This dataset presents experimental data on the release kinetics of curcumin and piperine from native and acetylated cassava starch nanoparticles into simulated gastrointestinal media. The nanoparticles were synthesized via nanoprecipitation and chemical acetylation, followed by encapsulation of curcumin, piperine, or their combination. Release experiments were performed under controlled conditions using simulated gastric fluid (pH 2, pepsin) and simulated intestinal fluid (pH 8, pancreatin and bile salts). Samples were incubated at 37°C in a shaking water bath, withdrawn at fixed time intervals, cooled, centrifuged, and analyzed by UV–Vis spectrophotometry at 430 nm and 344 nm for curcumin and piperine, respectively. The dataset includes raw absorption data, processed release percentages, and tabulated kinetic profiles for each formulation. Data are stored in a structured repository with clearly labeled folders and files, facilitating direct access and reuse. This dataset is valuable for researchers interested in nanomaterials, drug delivery, and functional food systems, providing a reference for kinetic modeling, reproducibility, and comparative studies across different nanoparticle carriers.
Rosero-Posso et al. (2026) studied this question.