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February 26, 20260 citations

The relationship between MMP-2 and TIMP-2 gene polymorphisms and skin barrier function, inflammatory cytokine levels in acne patients.

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SHSuling HuangLFLijia FangMZMeina Zhang

Key Points

  • The research aims to explore how specific gene polymorphisms affect skin barrier function and inflammation in acne patients.
  • Analyzed gene polymorphisms of MMP-2 and TIMP-2 in acne patients
  • Measured skin barrier function
  • Assessed inflammatory cytokine levels
  • Identified significant associations between MMP-2 polymorphisms and skin barrier function
  • Found correlations between TIMP-2 polymorphisms and inflammatory cytokine levels

Abstract

http://www.clinicaltrials.gov identifier is NCT07069075.

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Cite This Study

Huang et al. (2026) studied this question.

synapsesocial.com/papers/699fe39d95ddcd3a253e7956https://doi.org/10.1080/1744666x.2026.2636646
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reappraisal of Acne vulgaris Pathogenesis: The Role of TIMP-22025
  2. 2T-cell immunoglobulin and mucin domain-containing protein 3–mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne2025
  3. 3T-cell immunoglobulin and mucin domain-containing protein 3–mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne2025
  4. 4Identification of TIMP2 as a Prognostic Biomarker and Its Correlation with Tumor Immune Microenvironment: A Comprehensive Pan-Cancer Analysis2022 · 7 citations
  5. 5Analysis of MMP‐7 and TIMP‐2 gene polymorphisms in coronary artery disease and myocardial infarction: A Turkish case‐control study2017 · 17 citations