Regulatory T cells and plasmacytoid dendritic cells in drug rash with eosinophilia and systemic symptoms VS maculopapular drug eruption: A serological pilot study

Key Points

• This research explores the involvement of Treg cells and pDCs in DRESS/DIHS and MPE pathogenesis.
• Analyzed fluctuations in Treg and pDC percentages across different stages of DRESS/DIHS and MPE.
• Conducted serological assessments to measure cell populations and inflammation levels.
• Identified changes in Treg and pDC levels corresponding to the severity stages of both conditions.
• Increased circulating Treg cells linked to reduced inflammation in both DRESS/DIHS and MPE.