Andersen-Tawil syndrome (ATS) is a rare autosomal dominant genetic disorder. Its main clinical manifestations include severe ventricular arrhythmias (VA), periodic paralysis, and facial and skeletal dysplasia. Due to the lack of awareness of this disease, it is highly prone to missed diagnosis and misdiagnosis. This case report presents a young female who presented with abnormal electrocardiogram during physical examination, had poor efficacy after radiofrequency ablation treatment, and was finally diagnosed with Andersen-Tawil syndrome (ATS) by genetic testing, providing a reference for the diagnosis and treatment of this rare clinical disease.
Feng et al. (Wed,) studied this question.