Elinzanetant: Efficacy and safety in the management of vasomotor symptoms in postmenopausal women, a systematic review and meta-analysis with grading of recommendations assessment, development, and evaluation assessment.

Key Points

• The study aims to evaluate the efficacy and safety of elinzanetant in managing vasomotor symptoms in postmenopausal women.
• Conducted a systematic review of existing literature
• Performed a meta-analysis to combine data from different studies
• Graded recommendations using the GRADE approach
• Elinzanetant demonstrated significant efficacy in reducing vasomotor symptoms
• Safety profile was favorable with minimal adverse effects noted
• Recommendations for use were assessed as strong based on evidence quality