Longitudinal monitoring of tau aggregation in progressive supranuclear palsy with 18FPI-2620 PET.

Key Points

• This research aims to track tau aggregation patterns in progressive supranuclear palsy using PET imaging.
• Utilized [18F]PI-2620 PET imaging for longitudinal monitoring.
• Focused on individuals diagnosed with progressive supranuclear palsy.
• Analyzed tau progression over different disease stages.
• Detected tau aggregation using PET imaging.
• Observed network-based propagation of tau throughout the progressive supranuclear palsy stages.
• Noted saturation of tau in advanced stages.