Invasive yeast infection in paediatric acute lymphoblastic leukaemia: A report from the multi-international clinical trial AIEOP-BFM ALL 2009.

Key Points

• To investigate the incidence and outcomes of invasive yeast infections during treatment for acute lymphoblastic leukaemia in children.
• Prospective data collected from a large randomized multi-international leukaemia trial.
• Focused on children with acute lymphoblastic leukaemia receiving induction chemotherapy.
• Monitored occurrences of invasive yeast infections and associated outcomes.
• Found an incidence rate of 1.1% for invasive yeast infections in the study population.
• Infections primarily occurred during induction chemotherapy as bloodstream infections.
• The attributable mortality rate for these infections was noted to be 5.9%.