Comparing Efficacy and Safety of Bridging Therapy Versus Endovascular Thrombectomy in Acute Basilar Artery Occlusion: A Systematic Review and Meta-Analysis.

Key Points

• This research aims to compare the effectiveness and safety of intravenous thrombolysis before endovascular thrombectomy in cases of acute basilar artery occlusion.
• Conducted a systematic review and meta-analysis of existing studies on bridging therapy and endovascular thrombectomy.
• Evaluated outcomes related to functional recovery and mortality rates.
• Assessed the hemorrhage risk associated with both treatment methods.
• IV thrombolysis before thrombectomy improved functional outcomes without increasing the risk of hemorrhage.
• Mortality rates were lower in the intravenous thrombolysis group compared to thrombectomy alone.
• Successful recanalization rates were similar between the two treatment groups.