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February 27, 20261 citations

Functional Changes in the Glymphatic System in Children With Sensorineural Hearing Loss: A Study of Diffusion Tensor Imaging.

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JWJin WangJZJiayan ZhuangKLKevin Li

Key Points

  • To investigate functional changes in the glymphatic system in children with sensorineural hearing loss (SNHL).
  • Assessed glymphatic function using diffusion tensor imaging (DTI) and FW mapping.
  • Focused on children with SNHL, particularly those older than 3 years.
  • Evaluated potential connections between SNHL and cerebral clearance dysfunction.
  • Children with SNHL showed signs of compromised cerebral glymphatic function.
  • Indications of interstitial fluid retention were observed.
  • Integration of DTI-ALPS with FW mapping improved evaluation accuracy.

Abstract

Children with SNHL (especially those over 3 years old) might exhibit compromised cerebral glymphatic function, possibly attributable to clearance dysfunction and interstitial fluid (ISF) retention. Despite the recognized limitation of DTI-ALPS, its integration with FW mapping may enhance the noninvasive indirect evaluation of glymphatic function.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69a13571ed1d949a99abf48chttps://doi.org/10.1155/np/4484163
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