Prediction and Prognostication of Peripheral Blood Biomarkers in Head and Neck Cutaneous Squamous Cell Carcinoma.

Key Points

• This research aims to assess the prognostic value of peripheral blood biomarkers in cutaneous head and neck squamous cell carcinoma.
• Evaluated the correlation of preoperative peripheral blood biomarkers with tumor size and nodal burden.
• Analyzed the impact of Charlson Comorbidity Index and postoperative neutrophil-to-lymphocyte ratio on survival.
• Preoperative peripheral blood biomarkers showed a correlation with tumor size and nodal burden.
• High Charlson Comorbidity Index and low postoperative neutrophil-to-lymphocyte ratios were linked to lower survival rates.