Investigate the relationship between IL-38 gene polymorphisms and susceptibility to systemic lupus erythematosus (SLE).
Analyzed IL-38 gene polymorphisms (rs3811058 and rs7599662)
Established association with SLE susceptibility
Examined correlation with clinical and laboratory features
Identified significant association between IL-38 gene polymorphisms and SLE
Noted partial correlations with specific clinical features
Findings suggest broader implications for genetic susceptibility
Abstract
IL-38 gene polymorphisms (rs3811058 and rs7599662) are associated with SLE susceptibility, and are partially associated with clinical and laboratory features.