Brain Entropy and Complexity as Biomarkers of Neuroplasticity in Neurorehabilitation-A Scoping Review.

Key Points

• The study aims to explore brain entropy and complexity as indicators of neuroplasticity relevant to neurorehabilitation.
• Conducted a scoping review of existing literature on brain metrics and neuroplasticity, focusing on physiotherapy contexts.
• Analyzed how brain entropy and complexity relate to clinical outcomes in rehabilitation.
• Assessed the potential for these biomarkers to aid in personalized rehabilitation.
• Brain entropy and complexity metrics are sensitive to neuroplastic changes during rehabilitation.
• These measures may complement traditional clinical outcomes, enhancing monitoring of intervention responses.
• Standardization and longitudinal validation are needed before integrating these biomarkers into routine clinical practice.

Abstract