Positional isomerization of N-allyl compounds with a practical low-valent cobalt catalyst system

Key Points

• The aim is to develop a low-valent cobalt catalyst system for the positional isomerization of N-allyl compounds.
• Used commercially available and stable reagents
• Conducted (E)-stereoselective synthesis
• Focused on enamides and N-alkenyl heterocycles
• Successfully achieved positional isomerization
• Demonstrated the practicality of the catalyst system
• Showed selectivity towards (E)-enamides